Ten pairs of Locators were tested with interimplant divergences of 0°, 10°, and 20°. Scanning electron microscopy (SEM) was used to examine surface changes of the components. The results were tested with ANOVA and Bonferroni post hoc correction when normally distributed. Results CT99021 that were not normally distributed were tested with Kruskal-Wallis one-way ANOVA by ranks. At the start of the experiment the 10° group showed significantly more retention than the 0° group, but no

significant difference was found between the 0° and 20° groups or the 10° and 20° groups. After 5500 cycles, there was no significant difference in retention between any of the groups. The SEM images showed an approximately equal amount of wear in the nylon patrix inserts from all the groups. The retention of Locator pairs was not impaired by interimplant divergence of up to 20°. Retention after 5500 removal cycles was less than the initial retention in all groups.

The nylon Locator patrices showed wear defects of similar location, type, and magnitude in the SEM images, regardless of interimplant angulation. “
“Denture stomatitis, a common disorder affecting denture wearers, is characterized as inflammation and erythema of the oral mucosal areas covered by the denture. Despite its commonality, the etiology of denture stomatitis is not completely understood. A search C59 wnt of the literature was conducted in the PubMed electronic database (through November 2009) to identify relevant articles for inclusion in a review updating information on the epidemiology and etiology of denture stomatitis and the potential role of denture materials in this disorder. Epidemiological studies report prevalence of denture stomatitis among denture wearers

to range from 15% to over 70%. Studies have been conducted among various population samples, and this appears to influence prevalence rates. In general, where reported, incidence of denture stomatitis is higher among elderly denture users and among 上海皓元医药股份有限公司 women. Etiological factors include poor denture hygiene, continual and nighttime wearing of removable dentures, accumulation of denture plaque, and bacterial and yeast contamination of denture surface. In addition, poor-fitting dentures can increase mucosal trauma. All of these factors appear to increase the ability of Candida albicans to colonize both the denture and oral mucosal surfaces, where it acts as an opportunistic pathogen. Antifungal treatment can eradicate C. albicans contamination and relieve stomatitis symptoms, but unless dentures are decontaminated and their cleanliness maintained, stomatitis will recur when antifungal therapy is discontinued. New developments related to denture materials are focusing on means to reduce development of adherent biofilms. These may have value in reducing bacterial and yeast colonization, and could lead to reductions in denture stomatitis with appropriate denture hygiene.