Mutat Res 2002, 513: 37–48.PubMed 50. Loft S, Svoboda P, Kasai H, Tjønneland A, Vogel U, Møller P, Overvad K, Raaschou-Nielsen O: Prospective study of 8-oxo-7,8-dihydro-2′-deoxyguanosine

excretion and the risk of lung cancer. Carcinogenesis 2006, 27: 1245–1250.PubMedCrossRef 51. Elahi A, Zheng Z, Park J, Eyring K, McCaffrey T, S63845 concentration Lazarus P: The human OGG1 DNA repair enzyme and its association with orolaryngeal cancer risk. Carcinogenesis 2002, 23: 1229–1234.PubMedCrossRef 52. Aka P, Mateuca R, Buchet JP, Thierens H, Kirsch-Volders M: Are genetic polymorphisms in OGG1, XRCC1 and XRCC3 genes predictive for the DNA strand break repair phenotype and genotoxicity in workers exposed to low dose ionising radiations? Mutat Res 2004, 556: 169–181.PubMed 53. Dherin C, Radicella JP, Dizdaroglu M, Boiteux S: Excision of oxidatively damaged DNA bases by the human alpha-hOgg1 protein and the polymorphic alpha-hOgg1(Ser326Cys) protein which is frequently found in human populations. Nucleic Acids Res 1999, 27: 4001–4007.PubMedCrossRef 54. Park YJ, Choi EY, Choi JY, Park JG, You HJ, Chung MH: Genetic changes of hOGG1 and the activity of oh8Gua glycosylase in colon cancer. Eur J Cancer 2001, 37: 340–346.PubMedCrossRef 55. Boiteux S, Radicella JP: The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis. Arch Biochem Biophys 2000, 377: 1–8.PubMedCrossRef 56. Cho EY, Hildesheim A, Chen CJ, Chen IH, Mittl BF, Levine PH, Liu MY, Chen

JY, Brinton LA, Cheng YJ, Yang CS: Nasopharyngeal carcinoma and genetic polymorphisms of DNA repair enzymes XRCC1 and hOGG1. Cancer Epidemiol Biomarkers Prev 2003, 12: 1100–1104.PubMed 57. Görgens H, Müller A, Krüger PCI-34051 molecular weight S, Kuhlisch

E, König IR, Ziegler A, Schackert HK, Eckelt U: Analysis of the base excision repair genes MTH1, OGG1 and MUTYH in patients with squamous oral carcinomas. Oral Oncol 2007, 43: 791–795.PubMedCrossRef 58. Tse D, Zhai R, Zhou W, Heist RS, Asomaning K, Su L, Lynch TJ, Wain JC, Christiani DC, Liu G: Polymorphisms of the NER pathway genes, ERCC1 and XPD are associated with esophageal adenocarcinoma risk. Cancer Causes Control 2008, 19: 1077–1083.PubMedCrossRef the 59. Li H, Hao X, Zhang W, Wei Q, Chen K: The hOGG1 Ser326Cys polymorphism and lung cancer risk: a meta-analysis. Cancer Epidemiol Biomarkers Prev 2008, 17: 1739–1745.PubMedCrossRef 60. Garte S, Taioli E, Raimondi S, Paracchini V, Binkova B, Sram RJ, Kalina I, Popov TA, Singh R, Farmer PB: Effects of metabolic genotypes on intermediary biomarkers in subjects exposed to PAHS: results from the EXPAH study. Mutat Res 2007, 620: 7–15.PubMed 61. Marczynski B, Rihs HP, Rossbach B, Hölzer J, Angerer J, Scherenberg M, Hoffmann G, Brüning T, Wilhelm M: Analysis of 8-oxo-7,8-dihydro-2′-deoxyguanosine and DNA strand breaks in white blood cells of www.selleckchem.com/products/az628.html occupationally exposed workers: comparison with ambient monitoring, urinary metabolites and enzyme polymorphisms. Carcinogenesis 2002, 23: 273–281.PubMedCrossRef 62.