In phase I, cell growth was accelerated by maintaining high DO (>70%) with a constant stirring speed of 800 rpm. In phase II, PMLA production was increased by controlling DO at 70% using the automatically controlled stirring speed. In phase III, PMLA production on per gram of glucose (Yp/s) was enhanced by keeping DO at 70%, and using a low stirring speed to Tipifarnib molecular weight decrease cell growth. Compared with batch cultures, a higher PMLA yield was obtained with this strategy, i.e. PMLA production and Yp/s increased by 15% and 18%, respectively. CONCLUSION: Control strategies for pH, DO and stirring speed provide a good reference for process development and optimization
of PMLA production. (c) 2012 Society of Chemical
“The optical properties of shape-engineered InAs/InAlGaAs quantum dots (SEQDs) were investigated by temperature-dependent and excitation-power-dependent photoluminescence (PL) spectroscopy and compared with those of the conventionally grown InAs QDs (CQDs). The emission wavelength of the InAs/InAlGaAs SEQDs at 240 K was redshifted by 18 nm from that at 15 K, which was relatively smaller than that of the InAs CQDs (97 nm). The PL yield at 240 K was reduced to 1/86 and 1/65 of that measured at 15 K for the InAs CQDs and the InAs/InAlGaAs SEQDs, respectively. The emission wavelength for the InAs CQDs was blueshifted by 76 nm with increasing excitation power from 0.56 to 188 mW, compared to only by 7 nm for the InAs/InAlGaAs SEQDs. These results Epigenetic high throughput screening indicated that the InAs/InAlGaAs SEQDs were optically more stable than the InAs CQDs mainly due to the enhancement of the TGF-beta inhibitor carrier confinement in the vertical direction and the improvement in the size uniformity.”
“BACKGROUND: Literature regarding the outcomes of revision rotator cuff repair is limited. The purposes of the present study were to report the tendon repair integrity and clinical outcomes for a cohort of patients following revision arthroscopic
rotator cuff repair and to examine factors related to tendon healing and the influence of healing on clinical outcomes.
METHODS: Twenty-one of twenty-nine consecutive revision arthroscopic rotator cuff repairs with a minimum of two years of postoperative follow-up were retrospectively reviewed. Outcomes were evaluated on the basis of a visual analog pain scale, the range of motion of the shoulder, the Simple Shoulder Test, the American Shoulder and Elbow Surgeons score, and the Constant score. Ultrasonography was used to examine repair integrity at a minimum of one year following surgery. Ten shoulders underwent arthroscopic repair of a recurrent single-tendon posterior rotator cuff tear, whereas eleven shoulders had repair of both the supraspinatus and infraspinatus.
RESULTS: The mean age of the twenty-one subjects was 55.6 years; thirteen subjects were male and eight were female.