Clinical examinations were performed

pre- and postoperatively (3 month and after 1 year after surgery) in all patients.

Results: No intra-or postoperative complications were observed. The hypophysis ring curettes facilitated the preparation of the styloid process to the skull base.

Conclusions: The transoral, retromolar, para-tonsillar approach is a secure and fast method to resect an elongated symptomatic styloid process. Side effects of the classical transoral trans-tonsillar approach did not occur.”
“Self-drilling screws (SDS) and self-tapping screws (STS) allow for quicker bone insertion and are associated find more with increased anchorage. This is an experimental in vivo comparison of anterior cervical SDS and STS in the post-insertion acute and chronic phases.

Thirty C2-C6 vertebrae from six Santa Ins hair sheep were used. Each screw design was randomly assigned to five of each spinal level. Insertion torque was measured using a torque device. Three animals were killed in each phase. Vertebrae were randomly assigned to pullout tests and histomorphometrical bone-screw interface evaluation (percent screw-bone contact and bone density inside and outside the threaded area). Statistical significance was set at P < 0.05.

SDS insertion torque was greater than STS (P = 0.0001). SDS pullout strength was significantly greater than STS in the acute and chronic phases (P = 0.0001, 0.0003, respectively).

SDS percent screw-bone contact and inside area bone density were significantly greater in both phases. No outside area bone density differences were SB273005 ic50 observed in either phase.

SDS had higher insertion torque and better anchorage than STS in both phases. SDS percent bone-screw contact and inside area bone density were higher in both phases.”
“With the failure of so many pre-clinical

stroke studies to translate into the clinic, there is a need to find new therapeutics to minimize the extent of cellular damage and aid in functional recovery. Domain V (DV), the c-terminal protein fragment of the vascular basement membrane component, Entinostat perlecan, was recently shown to afford significant protection in multiple transient middle cerebral artery occlusion stroke models. We sought here to determine whether DV might have similar therapeutic properties in a focal photothrombosis stroke model in both young and aged mice. Young (3-month old) and aged (24-month old) mice underwent photothrombotic stroke to the motor cortex and were then treated with DV or phosphate buffered saline vehicle at different initial time points up to 7 days. Stroke volume was analyzed histologically using cresyl violet and functional recovery assessed behaviorally on both the grid-walking and cylinder tasks. In young mice, DV administration resulted in a significant decrease in infarct volume when treatment started 3 or 6 h post-stroke. In aged mice, DV administration was only protective when started 3 h post-stroke.