campestris pv. vesicatoria compared to X. oryzae pv. oryzae, A. tumefaciens, P. syringae and E. carotovora. The tested phytopathogenic bacteria employed

in the antibacterial assay showed significant degree of inhibition against the tested solvent extracts of C. lanceolatus except R. solanacearum. Antibiotics streptocyclin did not show any inhibition whereas tetracycline showed moderate antibacterial activity against the tested phytopathogens. Furthermore, petroleum ether, chloroform and methanol extracts displayed significant inhibitory activity against the test bacteria when compared to ethyl-acetate extract. Leaf extract with different solvents expressing potent inhibitory activity were further subjected to MIC assay. Petroleum ether, chloroform and methanol extract showed MIC value of 0.156 mg/ml against S. BKM120 in vitro selleck kinase inhibitor aureus and P. mirabilis. The ethyl-acetate extract showed the lowest MIC value 0.156 mg/ml against P. mirabilis. The MIC value ranged from 0.62 to 5 mg/ml against B. subtilis, E. coli and P. aeruginosa in all test extracts.

Gentamycin showed least MIC at 0.156 mg/ml against S. aureus and P. mirabilis followed by B. subtilis, E. coli, B. cereus, L. monocytogenes, S. flexineri, V. parahaemolyticus, and P. aeruginosa which varied from 0.31 to 2.5 mg/ml. The phytopathogenic bacteria viz., X. axonopodis pv. malvacearum, X. campestris pv. vesicatoria and P. syringae showed MIC of 0.156 mg/ml in petroleum ether extract. Chloroform leaf Resminostat extract showed MIC of 0.156 mg/ml against X. axonopodis pv. malvacearum and X. campestris pv. vesicatoria. MIC value of ethyl-acetate and methanol extracts varied from 6.25 to 5 mg/ml against all the test phytopathogens. Streptocyclin did not show any antibacterial activity whereas tetracycline showed MIC value ranged from 1.25 to 5 mg/ml against A.

tumefaciens and E. carotovora whereas did not show any significant activity against P. syringae, R. solanacearum, X. axonopodis pv. malvacearum, X. campestris pv. vesicatoria and X. oryzae pv. oryzae. The plant kingdom represents an enormous reservoir of biologically active compounds with various chemical structures and disease preventive properties. Herbal medicine has been a considerable revival of interest during the past few decades and still occupies a very important place in the developing world. Traditionally, local communities worldwide are extremely knowledgeable about local plants and other natural resources, on which they are so admiringly dependent. Today, many indigenous herbal remedies remain largely undocumented or recognized as potential forms of treatment and consequently continue to be used by only small groups of indigenous populations.24 It is a well-established fact that plant-derived compounds offer potential sources of new antibiotics, anticancer agents, and anti-HIV agents among other pharmaceutical agents.