Muscle torques and power output developed on a cycle ergometer showed significant positive correlations with the mesomorphic component while significant Belinostat fda negative ones with ectomorphy. Acknowledgments The study was supported by Ministry of Science and Higher Education (Grant No. AWF – Ds.-134).
The aim of the present study was to evaluate the basic and evoked blood flow in the skin microcirculation of the hand, one day and ten days after a series of 10 whole body cryostimulation sessions, in healthy individuals. The study group included 32 volunteers �C 16 women and 16 men. The volunteers underwent 10 sessions of cryotherapy in a cryogenic chamber. The variables were recorded before the series of 10 whole body cryostimulation sessions (first measurement), one day after the last session (second measurement) and ten days later (third measurement).

Rest flow, post-occlusive hyperaemic reaction, reaction to temperature and arterio�Cvenous reflex index were evaluated by laser Doppler flowmetry. The values recorded for rest flow, a post-occlusive hyperaemic reaction, a reaction to temperature and arterio �C venous reflex index were significantly higher both in the second and third measurement compared to the initial one. Differences were recorded both in men and women. The values of frequency in the range of 0,01 Hz to 2 Hz (heart frequency dependent) were significantly lower after whole-body cryostimulation in both men and women. In the range of myogenic frequency significantly higher values were recorded in the second and third measurement compared to the first one.

Recorded data suggest improved response of the cutaneous microcirculation to applied stimuli in both women and men. Positive effects of cryostimulation persist in the tested group for 10 consecutive days. Keywords: cryotherapy, skin blood flow, rest flow, post-occlusive hyperaemic reaction, arterio�Cvenous reflex index Introduction Whole body cryotherapy (WBCT) is more and more frequently used to complete pharmacotherapy and kinesiotherapy that are applied in rheumatologic and neurological diseases as well as in therapy of injuries of the locomotor system or in overload syndromes. It is also a modern, effective and safe procedure for athletes�� recovery (Hubbard et al., 2004).

The procedure of whole body cryostimulation is based on exposure of the organism to extremely low temperature (?110��C to ?160��C) for a very short period (1 �C 3 minutes) without provoking hypothermia or congelation (Westerlund et al., 2003). Cryogenic temperatures trigger physiological thermoregulation mechanisms, which results Carfilzomib in analgesic (Long et al., 2005; Brandner et al., 1996; Ingersoll et al., 1991), anti-inflammatory (Banfi et al., 2010; Knight, 1995), anti-oedematic (Meeusun et al., 1998) and anti-oxidative effects (Akhalaya et al., 2006; Dugue et al., 2005) and stimulate the immune system (Lubkowska et al., 2010b).