22% were classical SBP, 72% were CNNA and 6% were MNB. E. coli was the commonest organism isolated; all strains of it were resistant to third generation cephalosporins whereas 78% were resistant to quinolones.E. coli isolates were sensitive to imipenem, but only
67% were sensitive to a combination of third generation cephalosporin and beta lactamase inhibitor. Conclusion: SBP is common in patients with CL with ascites and is mostly caused by E coli. A high percentage of E coli are resistant to cephalosporins and quinolones, but sensitive to imipenem or a combination of 3rd generation cephalosporin VX-770 cost and beta lactamase inhibitor. Key Word(s): 1. SBP; 2. cirrhosis; 3. ascites; 4. antibiotic ; Presenting Author: LAURA MASALAITE Additional Authors: JONAS VALANTINAS, JUOZAS STANAITIS Corresponding Author: LAURA MASALAITE Affiliations: Clinic of gastroenterology, nephrourology and surgery, Medical Faculty, Vilnius University, Objective: Endoscopic band ligation (EBL) has a high tendency of variceal recurrence. The aim was to evaluate the value of esophageal collateral veins as predictors for variceal recurrence after EBL. Methods: 31 patient with large esophageal varices and EBL indicated were enrolled in prospective
TAM Receptor inhibitor study. Endosonography was performed before EBL and collateral CYTH4 veins were classified into three types (peri-esophageal
(peri-ECV), para-esophageal (para-ECV) and perforating veins) and two grades (mild and severe). Varices were ligated every 2 weeks until obliteration and upper endoscopy was performed every 3 month to detect any form of varices or red-color signs. Relationship between endosonography findings and the variceal recurrence rate was analysed (p value < 0,05 was considered statistically significant). Results: Variceal recurrence was detected in 5 patients (16,1%) within 3 months, in 8 patients (36,6%) within 6 months and in 12 patients (75%) within 12 month. 16 of the 31 patients were followed for 12 month and were divided into non-recurrence and recurrence (early and late) groups. No significant difference between these groups regarding collateral veins type and grade was found (table 1 and 2). Mathematical cox proportional hazards model of data found that severe peri-ECV are associatedwith higher and earlier recurrence risk after EBL (hazard ratio 1,57). Conclusion: Our study showed that endosonography findings does not predict variceal recurrence after EBL. Our results may be conflicting due to a small sample size and short follow up period. Key Word(s): 1. Esophageal varices; 2. Ligation; 3. Variceal recurrence; 4.