All subjects were healthy, and sexually active, without neurological diseases, genital, or urethral surgery and they were not under any medications. Subjects were evaluated with ultrasound, uroflowmetry, and post-void residual urine (PVR) measurement. All subjects selleck products were followed for 22 days (T) with daily uroflowmetry, and were instructed to ejaculate only on specific days (0, 6 and

22) during the study period. On days 0, 6 and 22 uroflow measurements were performed between 2 and 6 hr following ejaculation. Uroflowmetry parameters before and after ejaculation and during abstinence were compared. Data presented a non-normal distribution and the non-parametric Wilcoxon-match-paired test and Kruskal-Wallis test were used for statistical analysis. Results: 18 subjects (mean age 27.4years) completed the study. A total of 414 uroflow charts were collected. A statistical significant increase in Qmax was observed after ejaculation Ilomastat clinical trial (T-1 Qmax: 22.7 +/- 5.4 vs. T0 Qmax: 25.7 +/- 8, P = 0.002; T5 Qmax 23.2 +/- 5.4 vs. T6 Qmax 25.4 +/- 8, P = 0.031; T21 Qmax

21 +/- 4.8 vs. T22 Qmax 24.5 +/- 7.9, P = 0.031). Sexual abstinence resulted in a progressive, statistically significant decline in Qmax rates (T0 Qmax 25.7 +/- 8 vs. T5 23.2 +/- 5.4 P = 0.035; T6 Qmax 25.4 +/- 8 vs. T21 Qmax 21 +/- 4.8, P = 0.01). PVR did not change during the study period. Conclusions: Our results suggest that in young healthy men micturition might be influenced by ejaculation. Our findings, if confirmed in larger series of patients with LUTS, should support that sexual status and activity could represent an important confounding factor in the interpretation of uroflowmetry traces. Neurourol. Urodynam 30:1571-1575, 2011. (C) 2011 Wiley Periodicals, Inc.”
“Elucidation of the association between short sleep Ispinesib duration and elevated blood pressure has implications for assessing and managing hypertension in adults. Objective. To assess the relationship between sleep duration and blood pressure, and its role in the etiology of hypertension. Methods. On a systematic search from MEDLINE,

EMBASE, CINAHL, PEDro, PsychINFO and grey literature were included articles with participants over 18 years, reported sleep duration, measured blood pressure or diagnosed hypertension, and the relationship between sleep duration and blood pressure was analyzed. Results. Of 2522 articles initially identified, 11 studies met the inclusion criteria. Sample sizes ranged from 505 to 8860 (aged >= 0-98 years). Five studies (aged >= 58-60 years) determined that sleep duration and blood pressure were unrelated. In younger adults, five studies reported an association between short sleep duration and hypertension before adjustment for confounding variables; only the findings from one study remained significant after adjustment. Two studies supported a sex association; women who sleep less than 5-6 h nightly are at greater risk of developing hypertension. Conclusion.