There may have been a selection bias due to the nature of the institution and the characteristics

of the region where participants were recruited. The themes regarding non-attendance in this study are not applicable to pulmonary rehabilitation programs located in other settings, such as community-based programs conducted in health centres or community halls. As patients were excluded if they could not speak English this study may not be representative of all individuals within the community and may not reflect cultural reasons that may exist for non-attendance. The number of patients who took part in this project was relatively small, Bcl-2 apoptosis however no new themes were arising in the final interviews and thus saturation of data was assumed to be achieved. In conclusion, many individuals who elected not to take up a referral to pulmonary rehabilitation perceived that there would be no health benefits from undertaking the program. Transport and travel were important barriers to both uptake and completion, related to lack of transport, cost of travel, and poor mobility. Being unwell was an important limitation to completion of the program. Improving uptake and completion of pulmonary rehabilitation requires new methods for conveying the proven benefits of pulmonary rehabilitation to eligible patients, along with flexible program models that

improve access and consider comorbid disease. Ethics: The La Trobe University Faculty of Health Sciences Human Research Ethics Committee and the Alfred Health Human Research Ethics Committee approved this study. GPCR Compound Library in vitro Informed consent was gained from all patients before data collection began. Competing interests: None declared. “
“Summary of: Franklyn-Miller A et al (2011) Foot orthoses in the prevention of injury in initial military training: a randomized controlled trial. Am J Sports Med 39: 30–37. [Prepared by Nicholas Taylor, CAP Co-ordinator. Question: Does the use of foot orthoses reduce injury rates in an at-risk military population? Design: Randomised, controlled not trial. Setting: A naval college in the United Kingdom. Participants: New-entry officer

cadets assessed as having medium to high risk according to plantar pressure deviations assessed during a walking task. Key exclusion criteria were pre-existing orthotic use, and lower limb injury within the last 6 months. Randomisation of 400 participants allocated 200 to the intervention group and 200 to a control group. Interventions: Both groups completed a progressive gym and running program, which included a minimum of 2 or 3 periods of physical training each day over a 7 week period. In addition, the intervention group received customised foot orthoses. The control group received neither a shoe insert nor an orthosis. Outcome measures: The primary outcome was lower limb overuse injury requiring removal from physical training for 2 or more days.