Results: Of 1766 patients referred, 79 patients

with variceal bleed were included in the analysis, after excluding those with 1) endoscopy elsewhere prior to admission (n = 2) 2) bleeding during admission (n = 11) & 3) incomplete or unreliable data (n = 7). Mortality was similar in patients who received endoscopy within 15 hours (8/62) compared to those that did not (1/17) (p = 0.675). Median TTE for patients who died was significantly shorter than for survivors (2.1 vs. 8.23 hours, p = 0.04). There was a moderate inverse correlation between TTE and the full Rockall score (rs = -0.519 p < 0.001), and a weaker inverse correlation with the pre-endoscopy Rockall Score (rs = -0.39, p < 0.001) and Glasgow Blatchford score (rs = -0.371, p = 0.011, n = 46). When adjusted for age, gender, presentation symptoms of either haematemesis Hydroxychloroquine molecular weight and/or melaena, blood transfusion, pre-endoscopy Rockall score and TTE, mortality was significantly increased only in patients with Child Pugh Class C (OR 12.3, 95% CI 1.21–125.2). Conclusion: Time to endoscopy does not affect mortality in patients with variceal bleeding. However, it is influenced by patient’s condition with patients with more severe disease or bleeding receiving endoscopy sooner. check details When adjusted for other factors,

Child Pugh Class C was the main risk factor for mortality. 1. Hsu YC, Chung CS, Tseng CH, Lin TL, Liou JM, Wu MS, Hu FC, Wang HP. Delayed endoscopy as a risk factor for in-hospital mortality in cirrhotic patients

with acute variceal hemorrhage. J Gastroenterol Hepatol 2009;24: 1294–1299. DR J HUNT AND DR J KOO Department of Gastroenterology and Hepatology, Liverpool Hospital NSW Introduction: The use of transcatheter arterial embolization (TAE) to control upper GI haemorrhage in those who have failed endoscopic treatment remains relatively uncommon, but is well recognised as a salvage procedure and alternative to surgery. This retrospective study examined C1GALT1 the outcomes of TAE over a 10 year period, as a second line therapy, in those assessed not suitable for surgery, for upper GI bleeding refractory to gastroscopic intervention. Results: The cohort numbered 16 patients; mean age 62 [range 20–85], 14/16 patients were male, 50% had a history of prior GI bleeding and 9/16 (56%) were on anti platelets or anticoagulation. Per patient; an average of 12 red cell units were transfused, average length of hospital stay was 37 days. 14 patients were admitted to intensive care. Endoscopy was performed within 24 hours in 11/16 (69%). At endoscopy; gastro-duodenal ulceration was found in 8/16 (50%), 5/16 (31%) had active bleeding and 5/16 (31%) had no identifiable source. 50% of gastroscopies resulted in interventional treatment with a combination of heater probe and or adrenaline.