Found: C, 79.11; Selleck NVP-BKM120 H, 5.57; N, 11.09; O, 4.20. (5-(4-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)(1H-indol-2-yl)methanone7g. Blackish, m.p: 182–184 °C; IR vmax (cm−1)*; 1H NMR (400 MHz, DMSO-d6) δ (ppm)#; 13C NMR (100 MHz, DMSO-d6) δ (ppm)#; MS (EI): m/z 400.92 (M+1)+. Anal. calcd. for C24H18ClN3O: C, 72.09; H, 4.54; N, 10.51; O, 4.00. Found: C, 72.09; H, 4.53; N, 10.50; O, 4.02. (1H-indol-2-yl)(5-phenyl-3-m-tolyl-4,5-dihydro-1H-pyrazol-1-yl)methanone7h. Yellowish, m.p: 176–178 °C; IR vmax (cm−1)*; 1H NMR (400 MHz, DMSO-d6) δ (ppm)#: 2.31 (s, 3H); 13C NMR (100 MHz, DMSO-d6) δ (ppm)#; MS (EI): m/z 380.40 (M+1)+. Anal. calcd. for C25H21N3O: C, 79.13; H, 5.58; N, 11.07; O, 4.22. Found: Ku-0059436 datasheet C, 79.16; H, 5.56; N, 11.05; O, 4.24. (5-(4-hydroxyphenyl)-3-m-tolyl-4,5-dihydro-1H-pyrazol-1-yl)(1H-indol-2-yl)methanone7i. Brownish, m.p: 189–191 °C; IR vmax (cm−1)*; 1H NMR (400 MHz, DMSO-d6) δ (ppm)#: 5.32 (s, 1H, –OH), 2.31 (s, 3H, –CH3); 13C NMR (100 MHz,
DMSO-d6) δ (ppm)#; MS (EI): m/z 396.51 (M+1)+. Anal. calcd. for C25H21N3O2: C, 75.93; H, 5.35; N, 10.63; O, 8.09. Found: C, 75.95; H, 5.36; N, 10.61; O, 8.11. (1H-indol-2-yl)(5-(4-methoxyphenyl)-3-m-tolyl-4,5-dihydro-1H-pyrazol-1-yl)methanone7j. Yellowish, m.p: 162–164 °C; IR vmax (cm−1)*; 1H NMR (400 MHz, DMSO-d6) δ (ppm)#: 3.85 (s, 3H, –OCH3), 2.32 (s, 3H, –CH3); 13C NMR (100 MHz, DMSO-d6) δ (ppm)#; MS (EI): m/z 410.52 (M+1)+. Anal. calcd. for C26H23N3O2: C, 76.26; H, 5.66; N, 10.26; O, 7.81. Found: C, 76.28; H, 5.64; N, 10.25; O, 7.83. (5-(4-hydroxy-3-methoxyphenyl)-3-m-tolyl-4,5-dihydro-1H-pyrazol-1-yl)(1H-indol-2-yl)methanone7k.
unless Light black, m.p: 156–158 °C; IR vmax (cm−1)*; 1H NMR (400 MHz, DMSO-d6) δ (ppm)#: 5.32 (s, 1H, –OH), 3.83 (s, 3H, –OCH3), 2.38 (s, 3H, –CH3); 13C NMR (100 MHz, DMSO-d6) δ (ppm)#; MS (EI): m/z 426.36 (M+1)+. Anal. calcd. for C26H23N3O3: C, 73.39; H, 5.45; N, 9.88; O, 11.28. Found: C, 73.37; H, 5.48; N, 9.86; O, 11.30. (1H-indol-2-yl)(3-m-tolyl-5-p-tolyl-4,5-dihydro-1H-pyrazol-1-yl)methanone7l. Reddish brown, m.p: 177–179 °C; IR vmax (cm−1)*; 1H NMR (400 MHz, DMSO-d6) δ (ppm)#: 2.31 (s, 6H, –CH3); 13C NMR (100 MHz, DMSO-d6) δ (ppm)#; MS (EI): m/z 394.52 (M+1)+. Anal. calcd. for C26H23N3O: C, 79.36; H, 5.89; N, 10.68; O, 4.07. Found: C, 79.37; H, 5.91; N, 10.69 O, 4.09.